The exhibition Gianfranco Baruchello. Possible Worlds presented a selection of works by the artist (Livorno, August 29, 1924 – Rome, January 14, 2023) both inside and outside Villa Farnesina, creating an unprecedented dialogue between contemporary art and Renaissance heritage.

The exhibition The Colors of Prosperity highlighted the Loggia of Cupid and Psyche with its extraordinary festoons depicting more than 170 botanical species, revealing new discoveries through innovative scientific analyses and interactive tools.

The exhibition Villa Farnesina 1927–1944 recounted the period when the villa served as the seat of the Royal Academy of Italy, documenting the restorations and transformations that marked its transition from a residence to a representative building.

The exhibition The Archaeological Excavation in the Garden of Palazzo Corsini presented the discovery of a Roman kiln dating from the 1st–3rd century AD and a deposit of amphorae, revealing the unusual presence of production facilities in the heart of Trastevere.

The exhibition The Centenary Triptych recounted the celebrations of Leonardo, Raphael, and Dante in the post–World War I period, between the memory of the past and new artistic languages, featuring works and materials that shaped twentieth-century art and culture.